Clinical Trial at AIIMS, New Delhi

Evaluation of ITIS Ayurvedic Eye Drops- a Polyherbal Formulation in the Management of Various Ophthalmic Disorders. A Prospective, Randomized, Open Labelled, Comparative Clinical Trial was conducted from May, 2007 to November, 2009 at Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences (AIIMS), New Delhi 110029, India.

Patients and Methodology of the Clinical Trial

Patients with allergic conjunctivitis visiting Dr. R. P. Center, OPD regularly enrolled in the study The grading of allergic conjunctivitis was observed through Slit lamp examination All patients randomly divided into two groups:
Group A receiving ITIS Eye Drops and
Group B receiving the reference drug (Olopatadine) Patients self-administered the assigned study agent:
Group A - ITIS Eye Drops four times daily to each eye for 21 days
GROUP B - Olopatadine two times daily to each eye for 21 days Patient’s follow-up after 1 week, 2 weeks and 3 weeks

Results & Conclusion:

ITIS Eye Drops found to as effective as Olopatadine In some cases, Polyherbal formulation (ITIS) showed more effectiveness in reducing itching and watery eyes as compared to Olopatadine No significant side effect was observed in Polyherbal formulation (ITIS) treated group; but in case of Olopatadine 3.33% of patients complained about some allergic reaction This study concluded that, ITIS Eye Drops play a significant role in the treatment of allergic conjunctivitis and eye fatigue without any side effects as that experienced with Olopatadine a standard anti-allergic and eye toning agent.

ITIS Clinical Trial at AIIMS, New Delhi